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CAS 2430-27-5 chemical formula,CAS 2430-27-5 MSDS,CAS 2430-27-5 chemical properties

CAS Number 2430-27-5
chem name 2-Propylvaleramide
formula C8H17NO
synonyms Valeramide,2-propyl- (6CI,7CI,8CI);2-Propylpentamide;Heptane-4-carboxamide;Depamide;Di-n-propylacetamide;Dipropylacetamide;a-Propylvaleramide;

CAS Number 2430-27-5 properties (MSDS)


The IUPAC name of this chemical is 2-Propylvaleramide. With the CAS registry number 2430-27-5 and EINECS registry number 219-394-2, it is also named as pentanamide, 2-propyl-. In addition, the molecular formula is C8H17NO and the molecular weight is 143.23. What's more, it should be stored in sealed container, and put in a cool and dry place.

Physical properties about this chemical are: (1)ACD/LogP: 1.77; (2)ACD/LogD (pH 5.5): 1.77; (3)ACD/LogD (pH 7.4): 1.77; (4)ACD/BCF (pH 5.5): 13.03; (5)ACD/BCF (pH 7.4): 13.03; (6)ACD/KOC (pH 5.5): 218.68; (7)ACD/KOC (pH 7.4): 218.68; (8)#H bond acceptors: 2; (9)#H bond donors: 2; (10)#Freely Rotating Bonds: 5; (11)Polar Surface Area: 20.31 Å2; (12)Index of Refraction: 1.44; (13)Molar Refractivity: 42.63 cm3; (14)Molar Volume: 161.7 cm3; (15)Polarizability: 16.9 ×10-24cm3; (16)Surface Tension: 31 dyne/cm; (17)Density: 0.885 g/cm3; (18)Flash Point: 119.9 °C; (19)Enthalpy of Vaporization: 51.3 kJ/mol; (20)Boiling Point: 274.6 °C at 760 mmHg; (21)Vapour Pressure: 0.00535 mmHg at 25°C.

Preparation of 2-Propylvaleramide: it can be prepared by methyl a-cyanopropylpentanoate through hydrolysis, decarboxylation and hydrolysis. The a-cyano normal propylpentanoate methyl can be obtained by methyl cyanoacetate through alkylation reaction.

Uses of 2-Propylvaleramide: it can be used in the treatment of various types of epilepsy. In addition, it can be used to get 2-propyl-valeric acid. This reaction is a kind of hydrolysis reaction. It will need reagent phthalic anhydride. The reaction time is 45 minutes at reaction temperature of 240-250 °C. The yield is about 92% with reaction pressure of 3040 Pa.

2-Propylvaleramide can be used to get 2-propyl-valeric acid

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful if swallowed. During using it, wear suitable protective clothing and gloves. In addition, do not breathe dust.

You can still convert the following datas into molecular structure:
(2)InChI: InChI=1/C8H17NO/c1-3-5-7(6-4-2)8(9)10/h7H,3-6H2,1-2H3,(H2,9,10)

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 438mg/kg (438mg/kg)   Zhongguo Yaoli Xuebao. Acta Pharmacologica Sinica. Chinese Journal of Pharmacology. Vol. 9, Pg. 37, 1988.
mouse LD50 oral 950mg/kg (950mg/kg)   "Pharmacodynamie de l'Acide Dipropylacetique Vol. -, Pg. 71, 1968.
rat LD50 oral 890mg/kg (890mg/kg)   "Pharmacodynamie de l'Acide Dipropylacetique Vol. -, Pg. 72, 1968.